TY - JOUR
T1 - Chlorpropamide‐Induced Syndrome of Inappropriate Antidiuretic Hormone Secretion
AU - TANAY, A.
AU - FIREMANN, Z.
AU - YUST, I.
AU - ABRAMOV, A. L.
PY - 1981/7
Y1 - 1981/7
N2 - The Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) is a rare but serious complication of chlorpropamide therapy. In 2 elderly women who had diabetes mellitus, the SIADH developed two months after the chlorpropamide dosage had been increased to 500 mg daily. The syndrome disappeared after withdrawal of the drug. In one of these patients, re‐administration of chlorpropamide resulted in recurrence of the SIADH. A review of the current literature disclosed certain common denominators, i.e., most of the patients are elderly women whose dosage of chlorpropamide was increased shortly before the development of the SIADH. 1981 The American Geriatrics Society
AB - The Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) is a rare but serious complication of chlorpropamide therapy. In 2 elderly women who had diabetes mellitus, the SIADH developed two months after the chlorpropamide dosage had been increased to 500 mg daily. The syndrome disappeared after withdrawal of the drug. In one of these patients, re‐administration of chlorpropamide resulted in recurrence of the SIADH. A review of the current literature disclosed certain common denominators, i.e., most of the patients are elderly women whose dosage of chlorpropamide was increased shortly before the development of the SIADH. 1981 The American Geriatrics Society
UR - http://www.scopus.com/inward/record.url?scp=0019506684&partnerID=8YFLogxK
U2 - 10.1111/j.1532-5415.1981.tb01277.x
DO - 10.1111/j.1532-5415.1981.tb01277.x
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AN - SCOPUS:0019506684
SN - 0002-8614
VL - 29
SP - 334
EP - 336
JO - Journal of the American Geriatrics Society
JF - Journal of the American Geriatrics Society
IS - 7
ER -
