Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity

Connor A. Tsuchida, Shouyue Zhang, Mohammad Saffari Doost, Yuqian Zhao, Jia Wang, Elizabeth O'Brien, Huan Fang, Cheng Ping Li, Danyuan Li, Zhuo Yan Hai, Jonathan Chuck, Julian Brötzmann, Araz Vartoumian, David Burstein, Xiao Wei Chen, Eva Nogales, Jennifer A. Doudna*, Jun Jie Gogo Liu*

*Corresponding author for this work

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Medicine & Life Sciences