Characterization of arterial stenosis and elasticity by analysis of high-frequency pressure wave components

Zehava Ovadia-Blechman, Shmuel Einav*, Uri Zaretsky, David Castel, Michael Eldar

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

We describe a novel method for assessing stenosis severity based on pressure wave measurements. Pressure waves for several degrees of stenosis at different distances proximal to the stenosis were recorded from in vitro and in vivo models. Signal analysis was performed using power spectral density, and radial compliance was also measured. Pressure wave components at the acoustic frequency band (400-2500 Hz) changed gradually and were dependent upon the distance from the stenosis and its severity. The shift of the pressure components could also demonstrate the elastic properties of tubes and arteries and explain the effect of a bifurcation in the system.

Original languageEnglish
Pages (from-to)375-393
Number of pages19
JournalComputers in Biology and Medicine
Volume33
Issue number4
DOIs
StatePublished - Jul 2003

Funding

FundersFunder number
Drown Foundation
Elizabeth and Nicholas Slezak, Center for Cardiac Research and Medical Engineering
Ministry of Science, Israel

    Keywords

    • Blood pressure
    • Compliance
    • Hemodynamics
    • Signal processing
    • Stenosis

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