@article{48b7221426d74201b9d81f9930596e1a,
title = "Changes in Internalizing Symptoms During the COVID-19 Pandemic in a Transdiagnostic Sample of Youth: Exploring Mediators and Predictors",
abstract = "The COVID-19 pandemic is a chronically stressful event, particularly for youth. Here, we examine (i) changes in mood and anxiety symtpoms, (ii) pandemic-related stress as a mediator of change in symptoms, and (ii) threat processing biases as a predictor of increased anxiety during the pandemic. A clinically well-characterized sample of 81 youth ages 8–18 years (M = 13.8 years, SD = 2.65; 40.7% female) including youth with affective and/or behavioral psychiatric diagnoses and youth without psychopathology completed pre- and during pandemic assessments of anxiety and depression and COVID-related stress. Forty-six youth also completed a threat processing fMRI task pre-pandemic. Anxiety and depression significantly increased during the pandemic (all ps < 0.05). Significant symptom change was partially mediated by pandemic stress and worries. Increased prefrontal activity in response to neutral faces pre-pandemic was associated with more intense parent-reported anxiety during the pandemic (all Fs(1.95,81.86) > 14.44, ps < 0.001). The present work extends existing knowledge on the mediating role of psychological stress on symptoms of anxiety and depression in youth.",
keywords = "Anxiety, Children and adolescence, Depression, Stress, Threat bias, fMRI",
author = "Haller, {Simone P.} and Camille Archer and Annie Jeong and Allison Jaffe and Jones, {Emily L.} and Anita Harrewijn and Reut Naim and Linke, {Julia O.} and Joel Stoddard and Brotman, {Melissa A.}",
note = "Publisher Copyright: {\textcopyright} 2022, This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply.",
year = "2024",
month = feb,
doi = "10.1007/s10578-022-01382-z",
language = "אנגלית",
volume = "55",
pages = "206--218",
journal = "Child Psychiatry and Human Development",
issn = "0009-398X",
publisher = "Kluwer Academic/Human Sciences Press Inc.",
number = "1",
}