Changes in affinity of IgM antibodies in amphibian larvae

L. Du Pasquier, J. Haimovich

Research output: Contribution to journalArticlepeer-review


The increase in affinity of anti‐2, 4‐dinitrophenyl (DNP) antibodies of IgM class in tadpoles was followed as a function of time after administration of antigen by the inhibition of inactivation of DNP‐bacteriophage T4. A 10‐fold increase in binding affinity was observed over a period of 3–4 weeks after injection.

Original languageEnglish
Pages (from-to)580-583
Number of pages4
JournalEuropean Journal of Immunology
Issue number8
StatePublished - Aug 1974
Externally publishedYes


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