Cervical intraepithelial neoplasia in pregnant patients with third trimester bleeding. Diagnosis by colposcopy and guided biopsies

H. Levavi, S. Friedman, B. Kaplan, A. Schachter, J. Faktor, J. Ovadia

Research output: Contribution to journalArticlepeer-review

Abstract

The incidence of squamous cell carcinoma of the cervix in Jewish women is one of the lowest in the world. Therefore, routine cytological screening is not practised in Israel. In an effort to establish selective high-risk groups for cervical screening we have examined 154 pregnant women with third trimester bleeding of non-placental origin for the prevalence of cervical intraepithelial neoplasia (CIN), and human papilloma virus (HPV) infection, compared with that of 154 3rd trimester pregnant patients without bleeding. All patients were evaluated by cytology and colposcopy. Guided biopsies were taken from all colposcopically suspected lesions. The prevalence of CIN in the study group was significantly higher than in the control group - 5.8% vs. 1.3% (p = 0.03) and that of HPV induced changes was 7.1% vs. 2.6% (p = 0.06). Colposcopy was found to be superior to cytology in detecting CIN and HPV in these women. It is concluded that pregnant women with 3rd trimester bleeding of non-placental origin constitute a high-risk group for cervical pathology and they should be screened by colposcopic examination to increase the detection rate.

Original languageEnglish
Pages (from-to)17-20
Number of pages4
JournalCervix and the Lower Female Genital Tract
Volume12
Issue number1
StatePublished - 1994

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