Cerebrospinal fluid ferritin in malignant CNS involvement

Gisele Zandman‐Goddard, Yaacov Matzner, Abraham M. Konijn, Chaim Hershko

Research output: Contribution to journalArticlepeer-review

Abstract

Cerebrospinal fluid (CSF) ferritin was measured in patients with benign inflammatory and noninflammatory neurologic disorders and in patients with malignant disease with and without documented central nervous system (CNS) involvement. CSF ferritin levels were increased in the majority of patients with inflammatory neurologic disease and in patients with malignant involvement of the CNS. In contrast, in patients with noninflammatory neurologic disorders and in malignant disease without CNS involvement, CSF ferritin levels were normal. These findings indicate that although the specificity of CSF ferritin measurement is limited, it is a highly sensitive test that may be useful in the initial evaluation of patients with malignant CNS involvement, and in assessing their response to therapy.

Original languageEnglish
Pages (from-to)1346-1349
Number of pages4
JournalCancer
Volume58
Issue number6
DOIs
StatePublished - 15 Sep 1986
Externally publishedYes

Fingerprint

Dive into the research topics of 'Cerebrospinal fluid ferritin in malignant CNS involvement'. Together they form a unique fingerprint.

Cite this