Cerebral thrombosis in a newborn with a congenital deficiency of antithrombin III

B. Brenner*, A. Fishman, D. Goldsher, D. Schreibman, S. Tavory

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

An Israeli Arab family with type I antithrombin III (AT‐III) deficiency with several affected symptomatic members in three generations is reported. The propositus presented with deep vein thrombosis and pulmonary emboli associated with gestation. The propositus infant presented at the age of 2 weeks with superior sagittal and rectus sinus thrombosis. Hereditary AT‐III deficiency should be considered in infants with cerebral thrombosis, especially if they have a family history of thromboembolism. The role of prophylactic therapy by AT‐III concentrates in these infants should be further assessed.

Original languageEnglish
Pages (from-to)209-211
Number of pages3
JournalAmerican Journal of Hematology
Volume27
Issue number3
DOIs
StatePublished - Mar 1988
Externally publishedYes

Keywords

  • antithrombin
  • pregnancy
  • thrombosis

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