Cerebral pathological and compensatory mechanisms in the premotor phase of leucine-rich repeat kinase 2 parkinsonism

Keyphrases

• Parkinsonism 100%
• Compensatory Mechanisms 100%
• Pathogenic Mechanism 100%
• Leucine-rich Repeat Kinase 2 (LRRK2) 100%
• Premotor Phase 100%
• Parkinson's Disease 66%
• G2019S mutation 50%
• Dorsal Premotor Cortex 50%
• Non-carriers 33%
• G2019S 33%
• Cerebral Activity 33%
• Caudate nucleus 33%
• Control Parameters 16%
• Increased Activity 16%
• Symptom Onset 16%
• Striatal 16%
• Between-group 16%
• First-degree Relatives 16%
• Mutation Carriers 16%
• Functional Magnetic Resonance Imaging 16%
• Ashkenazi Jews 16%
• Motor Control 16%
• Disease-related 16%
• Motor Symptoms 16%
• Early Markers 16%
• Motor Deficits 16%
• Sensory Regions 16%
• Patients with Parkinson's Disease 16%
• Early Disease 16%
• Effective Connectivity 16%
• Jewish Patients 16%
• Behavioral Performance 16%
• Cerebral Changes 16%
• Internal Selection 16%
• Cerebral Function 16%
• Laterality Judgment 16%
• Cerebral Mechanism 16%
• Long-range Connectivity 16%
• Movement-related Activity 16%
• Motor Representation 16%
• Extrastriate Body Area 16%
• Motor Imagery Task 16%
• Biomechanical Constraints 16%
• Imagined Movement 16%

Neuroscience

• Parkinsonism 100%
• Leucine Rich Repeat Kinase 2 100%
• Parkinson's Disease 83%
• Premotor Cortex 50%
• Caudate Nucleus 33%
• Hemispheric Dominance 16%
• Functional Magnetic Resonance Imaging 16%
• Brain Function 16%
• Motor Control 16%