A new way of inferring and presenting psychiatric signs and symptoms as a correlate of cerebral bioimpedance pattern is proposed. The basal principles of bioimpedance have been applied through promising techniques already developed and used. The biophysical electrical shunt model meets the fundamental criteria for static and dynamic regional extracellular fluid volume alterations and ionic density, velocity and compositional changes in the same spatial and temporal units. Bioimpedance technology applied by a suitable method can potentially utilize bioimpedance essentials to display high sensitivity and specificity resolution revealing regional extracellular iono-liquid disturbances in the brain. We suggest that the theoretical model for utilizing bioimpedance as a function for estimating psychiatric signs and symptoms may open new horizons in the neuroscience of biotyping mental disorders.