Cerebral and cardiac toxicity of a small dose of lignocaine

Herman O. Klein*, Itzhak Jutrin, Elieser Kaplinsky

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


A patient is reported in whom an intravenous bolus injection of 50 mg lignocaine produced extreme sinus bradycardia (rate 14 to 20/min). Only 2 patients with such a response to a similarly small dose have been previously reported, but these reports indicate clearly that careful electrocardiographic monitoring is advisable when lignocaine is administered.

Original languageEnglish
Pages (from-to)775-778
Number of pages4
Issue number7
StatePublished - 1975


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