Cell fusion and hybrids in Archaea: Prospects for genome shuffling and accelerated strain development for biotechnology

Adit Naor, Uri Gophna*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

34 Scopus citations

Abstract

The ability to exchange DNA between cells is a molecular process that exists in different species in the domain Archaea. Such horizontal gene transfer events were shown to take place between distant species of archaea and to result in the transfer of large genomic regions. Here we describe recent progress in this field, discuss the potential use of natural gene exchange processes to perform genome shuffling and argue its possible biotechnological applications.

Original languageEnglish
JournalBioengineered
Volume4
Issue number3
DOIs
StatePublished - May 2013

Keywords

  • Archaea
  • Cell fusion
  • Haloferax mediterranei
  • Haloferax volcanii
  • Sulfolobus

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