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Cell damage by excess CuZnSOD and down's syndrome
Y. Groner
*
,
O. Elroy-Stein
,
Karen Avraham
, M. Schickler
, H. Knobler
, D. Minc-Golomb
, O. Bar-Peled
, R. Yarom
, S. Rotshenker
*
Corresponding author for this work
Weizmann Institute of Science
Department of Pathology
Hebrew University of Jerusalem
Research output
:
Contribution to journal
›
Article
›
peer-review
72
Scopus citations
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Keyphrases
Cell Damage
100%
Down Syndrome
100%
Superoxide Dismutase
100%
CuZn
100%
Superoxide Dismutase Genes
62%
Gene Dosage
31%
Serotonin
25%
Transgenic
25%
Neuromuscular Junction
25%
Blood Platelets
18%
Dense Granules
18%
Transgenic Mice
12%
Etiology
12%
Overexpression
12%
Neurotransmitters
12%
Platelets
12%
Tongue
12%
Axon
12%
Neurotransmitter Uptake
12%
Chromaffin Granules
12%
Tongue muscles
12%
Growth Rate
6%
Morphological Changes
6%
Increased Activity
6%
Neuropathology
6%
Pathological Changes
6%
Accumulation Rate
6%
Overexpressing
6%
Transformant
6%
Transport System
6%
Cell Death
6%
Focus of Attention
6%
Superoxide Dismutase Activity
6%
Central Nervous System
6%
Chromosome 21
6%
Aged Mice
6%
Aged Rats
6%
Trisomy 21
6%
Nerve Growth Factor
6%
Entanglement
6%
Oxygen Radicals
6%
Clinical Symptoms
6%
PC12 Cells
6%
PC12
6%
Physiological Consequences
6%
Active Enzyme
6%
Reduced Rate
6%
Familial ALS
6%
Growth Response
6%
Transgenic Animals
6%
Pathological Abnormalities
6%
Housekeeping Proteins
6%
Symptom Patterns
6%
Synaptic Membrane
6%
Transport Mechanism
6%
Biogenic Amines
6%
Phenotypic Expression
6%
Transgenic Strains
6%
Elevated Levels
6%
Gene Encoding
6%
Neuronal Disorders
6%
Individuals with Down Syndrome
6%
Neuroscience
Superoxide Dismutase
100%
Down Syndrome
100%
Cell Damage
100%
Gene Dosage
31%
Platelet
31%
Serotonin
25%
Neuromuscular Junction
25%
Neurotransmitter
12%
Neurotransmitter Uptake
12%
Transgene
12%
Enzymes
12%
Axon
12%
Cell Death
6%
Central Nervous System
6%
Nerve Growth Factor
6%
Amyotrophic Lateral Sclerosis
6%
Chromosome 21
6%
Biogenic Amine
6%
Postsynaptic Membrane
6%
Free Radical
6%