TY - JOUR
T1 - Celiac Disease and Keratoconjunctivitis
T2 - Occurrence With Thrombocytopenic Purpura
AU - Eliakim, Rami
AU - Heyman, Samuel
AU - Kornberg, Abraham
PY - 1982/5
Y1 - 1982/5
N2 - A patient had a rare association of celiac disease, keratoconjunctivitis sicca, and autoimmune thrombocytopenia. Both the malabsorption and the thrombocytopenia responded to prednisone therapy. The development of three different autoimmune disorders in this patient may be related to the presence of HLA-B8 and HLA-Dw3, the prevalence of which is known to be increased in celiac disease and keratoconjunctivitis sicca and that of HLA-B8 in autoimmune thrombocytopenic purpura. Despite the fact that thrombocytopenia is rarely encountered in celiac disease, it is suggested that an autoimmune mechanism should be excluded in patients with this combination.
AB - A patient had a rare association of celiac disease, keratoconjunctivitis sicca, and autoimmune thrombocytopenia. Both the malabsorption and the thrombocytopenia responded to prednisone therapy. The development of three different autoimmune disorders in this patient may be related to the presence of HLA-B8 and HLA-Dw3, the prevalence of which is known to be increased in celiac disease and keratoconjunctivitis sicca and that of HLA-B8 in autoimmune thrombocytopenic purpura. Despite the fact that thrombocytopenia is rarely encountered in celiac disease, it is suggested that an autoimmune mechanism should be excluded in patients with this combination.
UR - http://www.scopus.com/inward/record.url?scp=0020035427&partnerID=8YFLogxK
U2 - 10.1001/archinte.1982.00340180195032
DO - 10.1001/archinte.1982.00340180195032
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AN - SCOPUS:0020035427
SN - 0003-9926
VL - 142
SP - 1037
JO - Archives of Internal Medicine
JF - Archives of Internal Medicine
IS - 5
ER -