Case report: Severe hyponatremia after water intoxication: A potential cause of rhabdomyolysis

Asher Korzets*, Yaacov Ori, Sharon Floro, Eitan Ish-Tov, Avri Chagnac, Talia Weinstein, Dina Zevin, Carlos Gruzman

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

A 28-year-old woman, treated for schizophrenia, developed severe hypotonic hyponatremia (serum Na: 109 mEq/L) after several days of compulsive water drinking. The patient was admitted in a coma and required intensive supportive therapy. Rhabdomyolysis quickly followed with high serum creatine phosphokinase levels and myoglobinuria. A high volume alkaline diuresis was initiated. Renal failure or compartment syndrome did not complicate the clinical picture. The mechanisms causing water intoxication and hyponatremia are discussed as are the possible pathogenetic explanations behind acute hyponatremia and rhabdomyolysis.

Original languageEnglish
Pages (from-to)92-94
Number of pages3
JournalAmerican Journal of the Medical Sciences
Volume312
Issue number2
DOIs
StatePublished - Aug 1996
Externally publishedYes

Keywords

  • Hyponatremia
  • Rhabdomyolysis
  • Water intoxication

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