Carriage of Colibactin-producing Bacteria and Colorectal Cancer Risk

Vadim Dubinsky, Iris Dotan, Uri Gophna*

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review


Colibactin is a genotoxic molecule, produced primarily by Escherichia coli. Colibactin causes DNA damage that may lead to colorectal cancer. Here we review recent advances in the study of colibactin and propose a focus on patients with inflammatory bowel diseases (IBD) who have higher levels of colibactin-producing bacteria in their intestines.

Original languageEnglish
Pages (from-to)874-876
Number of pages3
JournalTrends in Microbiology
Issue number11
StatePublished - Nov 2020


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