Caregiver willingness to vaccinate their children against COVID-19 after adult vaccine approval

International COVID-19 Parental Attitude Study (COVIPAS) Group

Research output: Contribution to journalArticlepeer-review

44 Scopus citations


Vaccines against COVID-19 are likely to be approved for children under 12 years in the near future. Understanding vaccine hesitancy in parents is essential for reaching herd immunity. A cross-sectional survey of caregivers in 12 emergency departments (ED) was undertaken in the U.S., Canada, and Israel. We compared reported willingness to vaccinate children against COVID-19 with an initial survey and post-adult COVID-19 vaccine approval. Multivariable logistic regression models were performed for all children and for those <12 years. A total of 1728 and 1041 surveys were completed in phases 1 and 2, respectively. Fewer caregivers planned to vaccinate against COVID-19 in phase 2 (64.5% and 59.7%, respectively; p = 0.002). The most significant positive predictor of willingness to vaccinate against COVID-19 was if the child was vaccinated per recommended local schedules. Fewer caregivers plan to vaccinate their children against COVID-19, despite vaccine approval for adults, compared to what was reported at the peak of the pandemic. Older caregivers who fully vaccinated their children were more likely to adopt vaccinating children. This study can inform target strategy design to implement adherence to a vaccination campaign.

Original languageEnglish
Article number10224
JournalInternational Journal of Environmental Research and Public Health
Issue number19
StatePublished - 1 Oct 2021


FundersFunder number
Danna Krupik
Department of Pediatric Emergency Medicine, New York Presbyterian Brooklyn Methodist Hospital
Departments of Paediatrics, Internal Medicine, Epidemiology & Biostatistics
Gualco Gianluca, Pediatric Emergency Department
Medicine & Dentistry, Women and Children’s Health Research Institute
Pediatric Institute of Italian part of Switzerland
Ran Goldman, The Pediatric Research in Emergency Therapeutics
Sant Joan de Déu Barcelona
St. Marianna University School of Medicine, Tokyo, Japan
Université de Montréal, Montréal, Québec, Canada
Ziv Medical Center, Israel
Children's Health Research Institute
University of Saskatchewan
Washington University School of Medicine in St. Louis
BC Children's Hospital
Children's Healthcare of Atlanta
University of Alberta
Sackler Faculty of Medicine, Tel-Aviv University
Schulich School of Medicine and Dentistry, Western University


    • COVID-19
    • Parental attitudes
    • Vaccine hesitancy


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