TY - JOUR
T1 - Cardiogenic Shock
T2 - Treatment
AU - Iakobishvili, Zaza
AU - Hasdai, David
PY - 2007/7
Y1 - 2007/7
N2 - The treatment of cardiogenic shock complicating the acute coronary syndromes consists of medical therapy, percutaneous revascularization procedures, cardiac surgery, and the implantation of devices. Medical therapy is limited to different positive inotropic and vasoactive drugs, without any firm evidence of survival benefit using these drugs. Several new pharmacologic compounds are at different stages of clinical research, but are not yet routinely approved for the treatment of cardiogenic shock. The only evidence-based therapy with proven survival benefit is timely revascularization. Intra-aortic balloon pump counterpulsation maintains its central role as supportive treatment in cardiogenic shock patients. Anecdotal evidence is available about the use of ventricular assist devices, cardiac resynchronization therapy, and emergent heart transplantation.
AB - The treatment of cardiogenic shock complicating the acute coronary syndromes consists of medical therapy, percutaneous revascularization procedures, cardiac surgery, and the implantation of devices. Medical therapy is limited to different positive inotropic and vasoactive drugs, without any firm evidence of survival benefit using these drugs. Several new pharmacologic compounds are at different stages of clinical research, but are not yet routinely approved for the treatment of cardiogenic shock. The only evidence-based therapy with proven survival benefit is timely revascularization. Intra-aortic balloon pump counterpulsation maintains its central role as supportive treatment in cardiogenic shock patients. Anecdotal evidence is available about the use of ventricular assist devices, cardiac resynchronization therapy, and emergent heart transplantation.
UR - http://www.scopus.com/inward/record.url?scp=34447309045&partnerID=8YFLogxK
U2 - 10.1016/j.mcna.2007.02.007
DO - 10.1016/j.mcna.2007.02.007
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C2 - 17640544
AN - SCOPUS:34447309045
SN - 0025-7125
VL - 91
SP - 713
EP - 727
JO - Medical Clinics of North America
JF - Medical Clinics of North America
IS - 4
ER -