TY - JOUR
T1 - Carcinoma of the clitoris
T2 - A histologic study with cytokeratin profile
AU - Czernobilsky, Bernard
AU - Gat, Andrea
AU - Evron, Rina
AU - Dgani, Ram
AU - Ben-Hur, Herzl
AU - Lifschitz-Mercer, Beatriz
PY - 1995/7
Y1 - 1995/7
N2 - A carcinoma of the clitoris showed a variety of histologic features not usually encountered in squamous cell carcinoma of the vulva. In addition to poorly differentiated nonkeratinizing squamous cell carcinoma, there were large areas showing a transitional cell carcinoma pattern, as well as foci of spindle and anaplastic cells. The clitoral neoplasm also differed in its cytokeratin (CK) profile from that described in invasive squamous cell carcinoma of the vulva, especially with regard to the widespread staining for CK 18 and 19 in the former. Thus, our study suggests that some carcinomas of the clitoris differ from those of ordinary squamous cell carcinomas of the vulva. More cases should be studied using immunohistochemical methods in order to establish the full histopathologic and CK range of the former.
AB - A carcinoma of the clitoris showed a variety of histologic features not usually encountered in squamous cell carcinoma of the vulva. In addition to poorly differentiated nonkeratinizing squamous cell carcinoma, there were large areas showing a transitional cell carcinoma pattern, as well as foci of spindle and anaplastic cells. The clitoral neoplasm also differed in its cytokeratin (CK) profile from that described in invasive squamous cell carcinoma of the vulva, especially with regard to the widespread staining for CK 18 and 19 in the former. Thus, our study suggests that some carcinomas of the clitoris differ from those of ordinary squamous cell carcinomas of the vulva. More cases should be studied using immunohistochemical methods in order to establish the full histopathologic and CK range of the former.
KW - Carcinoma
KW - Clitoris
KW - Cytokeratin
KW - Transitional cell carcinoma
UR - http://www.scopus.com/inward/record.url?scp=0029012404&partnerID=8YFLogxK
U2 - 10.1097/00004347-199507000-00014
DO - 10.1097/00004347-199507000-00014
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AN - SCOPUS:0029012404
SN - 0277-1691
VL - 14
SP - 274
EP - 278
JO - International Journal of Gynecological Pathology
JF - International Journal of Gynecological Pathology
IS - 3
ER -