TY - JOUR
T1 - Carboplatin-related idiosyncrasy
AU - Inbar, M.
AU - Merimsky, O.
AU - Chaitchik, S.
PY - 1995
Y1 - 1995
N2 - Side effects of cisplatin and carboplatin include nausea, vomiting, peripheral neuropathy, nephrotoxicity, hearing loss, bone marrow depression, and rarely Lhermitte's sign and allergic reactions. A unique case of idiosyncrasy related to carboplatin administration was observed in a young woman treated for ovarian cancer. Symptoms and signs included skin rash, shortness of breath, and redness of face and upper trunk, without drop in blood pressure or change in heart rate, and were resolved within a short time following administration of hydrocortisone and promethazine.
AB - Side effects of cisplatin and carboplatin include nausea, vomiting, peripheral neuropathy, nephrotoxicity, hearing loss, bone marrow depression, and rarely Lhermitte's sign and allergic reactions. A unique case of idiosyncrasy related to carboplatin administration was observed in a young woman treated for ovarian cancer. Symptoms and signs included skin rash, shortness of breath, and redness of face and upper trunk, without drop in blood pressure or change in heart rate, and were resolved within a short time following administration of hydrocortisone and promethazine.
KW - Carboplatin
KW - Idiosyncrasy
KW - Toxicity
UR - http://www.scopus.com/inward/record.url?scp=0029585919&partnerID=8YFLogxK
U2 - 10.1097/00001813-199512000-00010
DO - 10.1097/00001813-199512000-00010
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AN - SCOPUS:0029585919
VL - 6
SP - 775
EP - 776
JO - Anti-Cancer Drugs
JF - Anti-Cancer Drugs
SN - 0959-4973
IS - 6
ER -
