Carbapenem-resistant KPC-2-producing Escherichia coli in a Tel Aviv Medical Center, 2005 to 2008

Moran G. Goren, Shiri Navon-Venezia, Inna Chmelnitsky, Yehuda Carmeli*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

34 Scopus citations

Abstract

All of the carbapenem-resistant Escherichia coli (CREC) isolates identified in our hospital from 2005 to 2008 (n = 10) were studied. CREC isolates were multidrug resistant, all carried blaKPC-2, and six of them were also extended-spectrum beta-lactamase producers. Pulsed-field gel electrophoresis indicated six genetic clones; within the same clone, similar transferable blaKPC-2-containing plasmids were found whereas plasmids differed between clones. Tn4401 elements were identified in all of these plasmids.

Original languageEnglish
Pages (from-to)2687-2691
Number of pages5
JournalAntimicrobial Agents and Chemotherapy
Volume54
Issue number6
DOIs
StatePublished - Jun 2010

Funding

FundersFunder number
Seventh Framework Programme241796

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