Carbapenem-resistant Enterobacteriaceae: Biology, epidemiology, and management

Elizabeth Temkin; Amos Adler; Anat Lerner; Yehuda Carmeli

doi:10.1111/nyas.12537

Carbapenem-resistant Enterobacteriaceae: Biology, epidemiology, and management

Elizabeth Temkin, Amos Adler, Anat Lerner, Yehuda Carmeli^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Introduced in the 1980s, carbapenem antibiotics have served as the last line of defense against multidrug-resistant Gram-negative organisms. Over the last decade, carbapenem-resistant Enterobacteriaceae (CRE) have emerged as a significant public health threat. This review summarizes the molecular genetics, natural history, and epidemiology of CRE and discusses approaches to prevention and treatment.

Original language	English
Pages (from-to)	22-42
Number of pages	21
Journal	Annals of the New York Academy of Sciences
Volume	1323
Issue number	1
DOIs	https://doi.org/10.1111/nyas.12537
State	Published - 1 Sep 2014

Keywords

Antimicrobial resistance
Carbapenem-resistant Enterobacteriaceae
Carbapenemases
Infection control
Molecular genetics
Treatment

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/nyas.12537

Cite this

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abstract = "Introduced in the 1980s, carbapenem antibiotics have served as the last line of defense against multidrug-resistant Gram-negative organisms. Over the last decade, carbapenem-resistant Enterobacteriaceae (CRE) have emerged as a significant public health threat. This review summarizes the molecular genetics, natural history, and epidemiology of CRE and discusses approaches to prevention and treatment.",

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AU - Carmeli, Yehuda

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KW - Carbapenemases

KW - Infection control

KW - Molecular genetics

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Carbapenem-resistant Enterobacteriaceae: Biology, epidemiology, and management

Abstract

Keywords

UN SDGs

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