Cancer Stem Cells

David C. Taussig, Dominique Bonnet

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Original languageEnglish
Title of host publicationMolecular Hematology
Subtitle of host publicationThird Edition
PublisherWiley-Blackwell
Pages370-379
Number of pages10
ISBN (Print)9781405182317
DOIs
StatePublished - 10 Mar 2010
Externally publishedYes

Keywords

  • CSC hypothesis-implications for the way researchers approach malignant disease
  • CSC niche-Normal HSCs requiring support from non-hematopoietic cells for survival and function
  • Cancer stem cells
  • Cancer stem cells (CSCs), ability to produce all clonal cells
  • Evolution of hematological malignancy
  • Selective tyrosine kinase inhibitors (TKIs)
  • Targeting CSC signaling pathways
  • Targeting CSCs
  • Translocations and transcription factors in CSC generation

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