Cancer Incidence among Laboratory Workers in Biomedical Research and Routine Laboratories in Israel: Part I - The Cohort Study

Judith Shaham*, Rachel Gurvich, Yael Kneshet

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

Background: Laboratory work is associated with exposure to a mixture of carcinogens. Methods: The cohort is comprised of 4,300 laboratory workers. Cancer incidence was followed from 1960 to 1997. Results: A total of 230 cases were included in the cohort. The overall cancer standardized incidence ratio (SIR) was 1.04 (0.91-1.18). When a 20-year latency was introduced, SIR was increased significantly: 1.35 (1.13-1.61). Among routine workers and researchers, SIR was elevated significantly for the total population and for women, when a 20-year latency was introduced. SIR was also elevated significantly in research, routine, bacteriology and virology, and isotope laboratories. With respect to specific sites, significantly increased SIR was observed in breast, ovary, and thyroid cancer among women; and prostate cancer, leukemia, and melanoma among men. Conclusions: We suggest that work in research and biomedical laboratories might involve an increased risk of certain types of cancer.

Original languageEnglish
Pages (from-to)600-610
Number of pages11
JournalAmerican Journal of Industrial Medicine
Volume44
Issue number6
DOIs
StatePublished - Dec 2003
Externally publishedYes

Keywords

  • Breast cancer
  • Cancer
  • Carcinogens
  • Laboratory workers
  • Leukemia
  • Melanoma
  • Occupational cancer
  • Ovary cancer
  • Prostate cancer
  • Thyroid cancer

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