Can we apply gene therapy in the treatment of Parkinson patients?

B. A. Sela*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Problems associated with a long-term application of L-dopa to treat Parkinsons disease, have prompted interest in developing alternative therapeutic strategies. Parkinsons disease is a suitable candidate for neurological gene therapy, given our knowledge of the functional anatomy of the striato-nigral system. Recently, much effort was devoted to the administration of trophic factors to injured neurons, especially using glial cell line-derived factor (DGNF). Various aspects of this approach are discussed in this study.

Original languageEnglish
Pages (from-to)1168-1171, 1229
Issue number12
StatePublished - Dec 2001
Externally publishedYes


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