Can myometrial electrical activity identify patients in preterm labor?

Orli Most*, Oded Langer, Ram Kerner, Gal Ben David, Ilan Calderon

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

37 Scopus citations

Abstract

Objective: The objective of the study was to determine whether myometrial electrical activity can differentiate false from true preterm labor. Study Design: Electrical uterine myography (EUM) was measured prospectively on 87 women, gestational age less than 35 weeks. The period between contractions, power of contraction peaks and movement of center of electrical activity (RMS), was used to develop an index score (1-5) for prediction of preterm delivery (PTD) within 14 days of the test. The score was compared with fetal fibronectin (fFN) and cervical length (CL). Results: Patients delivering within 14 days from testing showed a higher index and mean RMS (P = .000). No patients with EUM index scores of 1-2 delivered in this time frame. Combining EUM with CL or fFN increased predictability. Logistic regression revealed that history of PTD and EUM index had 4- to 5-fold increased risk for PTD. Gestational age at testing, body mass index, fFN, and CL were nonsignificant contributors to PTD risk. Conclusion: Measuring myometrial electrical activity may enhance identification of patients in true premature labor.

Original languageEnglish
Pages (from-to)378.e1-378.e6
JournalAmerican Journal of Obstetrics and Gynecology
Volume199
Issue number4
DOIs
StatePublished - Oct 2008
Externally publishedYes

Keywords

  • electrical uterine myography index score
  • multichannel electromyography
  • premature labor

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