Can discordance in CRL at the first trimester predict birth weight discordance in twin pregnancies ?

Alina Weissmann-Brenner, Boaz Weisz, Reuven Achiron, Alon Shrim

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To examine the correlation between measurements of crown rump length (CRL), nuchal translucency (NT), and birth weight in dichorionic (DC) and monochorionic (MC) twin pregnancies. Methods: A retrospective analysis was performed on all twin term pregnancies delivered between 2001 and 2007 at the McGill University Health Center. Data collected included maternal age, CRL and NT measurement, results of glucose challenge test, birth weight and length, gestational age at delivery, and fetal gender. Results: The study population comprised 792 fetuses: 94 MC/ DA and 698 DC/DA. Maternal age, gestational age at delivery, birth weight, and birth length were all significantly higher for the DC group. Male fetuses had significantly higher NT and higher birth weight than female fetuses. Discordance in CRL was found to correlate with discordance in birth weight in the entire study population (P < 0.0001, R = 0.25), in the DC twins (P < 0.0001, R = 0.275), but not in MC twins (R = 0.10, P = 0.33). CRL discordance above the 90 th percentile ( > 12 % ) predicted 14/40 pregnancies with birth weight discordance above the 90 th percentile ( > 24 % ) [P < 0.001, LR = 4.1 (2.6 - 6.2)]. CRL discordance above the 95 th percentile ( > 16 % ) predicted

Original languageEnglish
Pages (from-to)489-493
Number of pages5
JournalJournal of Perinatal Medicine
Volume40
Issue number5
DOIs
StatePublished - Sep 2012
Externally publishedYes

Keywords

  • Birth weight
  • Crown rump length
  • Discordancy
  • Nuchal translucency
  • Twin pregnancy

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