@article{7695262cfbf8457296b8c85f26411a95,
title = "CAMTAs: Calmodulin-binding transcription activators from plants to human",
abstract = "Recently, a novel family of calmodulin-binding transcription activators (CAMTAs) was reported in various eukaryotes. All CAMTAs share a similar domain organization, with a novel type of sequence-specific DNA-binding domain (designated CG-1). This domain could bind DNA directly and activate transcription, or interact with other transcription factors, not through DNA binding, thus acting as a co-activator of transcription. Investigations of CAMTAs in various organisms imply a broad range of functions from sensory mechanisms to embryo development and growth control, highlighted by the apparent involvement of mammalian CAMTA2 in cardiac growth, and of CAMTA1 in tumor suppression and memory performance.",
keywords = "Calcium, Calmodulin, Hypertrophy, Signal transduction, Transcription factor, Tumor suppression",
author = "Aliza Finkler and Ruth Ashery-Padan and Hillel Fromm",
note = "Funding Information: We are grateful to Dr. Metsada Pasmanik-Chor from the Bioinformatics Unit of the George S. Wise Faculty of Life Sciences at Tel Aviv University, and Maya Schushan for their invaluable assistance in bioinformatics analysis. We also thank Dr. Nicolas Bouch{\'e} for critical reading of the manuscript. The research in the lab of R.A.-P. is supported by the AMN foundation, the Israel Science Foundation and the German-Israeli Foundation. Research of CAMTAs in the lab of H.F. is supported by the Israel Science Foundation (ISF), and the India-Israel Cooperation in Agricultural Biotechnology.",
year = "2007",
month = aug,
day = "21",
doi = "10.1016/j.febslet.2007.07.051",
language = "אנגלית",
volume = "581",
pages = "3893--3898",
journal = "FEBS Letters",
issn = "0014-5793",
publisher = "John Wiley and Sons Inc.",
number = "21",
}