Calmodulin-binding transcription activator (CAMTA) 3 mediates biotic defense responses in Arabidopsis

Yael Galon; Roy Nave; Joy M. Boyce; Dikla Nachmias; Marc R. Knight; Hillel Fromm

doi:10.1016/j.febslet.2008.02.037

Calmodulin-binding transcription activator (CAMTA) 3 mediates biotic defense responses in Arabidopsis

Yael Galon, Roy Nave, Joy M. Boyce, Dikla Nachmias, Marc R. Knight, Hillel Fromm^*

^*Corresponding author for this work

School of Plant Sciences and Food Security

Research output: Contribution to journal › Article › peer-review

Abstract

Calmodulin-binding transcription activator (CAMTA) 3 (also called SR1) is a calmodulin-binding transcription factor in Arabidopsis. Two homozygous T-DNA insertion mutants (camta3-1, camta3-2) showed enhanced spontaneous lesions. Transcriptome analysis of both mutants revealed 6 genes with attenuated expression and 99 genes with elevated expression. Of the latter, 32 genes are related to defense against pathogens (e.g. WRKY33, PR1 and chitinase). Propagation of a virulent strain of the bacterial pathogen Pseudomonas syringae and the fungal pathogen Botrytis cinerea were attenuated in both mutants. Moreover, both mutants accumulated high levels of H₂O₂. We suggest that CAMTA3 regulates the expression of a set of genes involved in biotic defense responses.

Original language	English
Pages (from-to)	943-948
Number of pages	6
Journal	FEBS Letters
Volume	582
Issue number	6
DOIs	https://doi.org/10.1016/j.febslet.2008.02.037
State	Published - 19 Mar 2008

Keywords

Calcium
Calmodulin
Pathogens
Reactive oxygen species
Signal transduction
Transcriptome

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10.1016/j.febslet.2008.02.037

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title = "Calmodulin-binding transcription activator (CAMTA) 3 mediates biotic defense responses in Arabidopsis",

abstract = "Calmodulin-binding transcription activator (CAMTA) 3 (also called SR1) is a calmodulin-binding transcription factor in Arabidopsis. Two homozygous T-DNA insertion mutants (camta3-1, camta3-2) showed enhanced spontaneous lesions. Transcriptome analysis of both mutants revealed 6 genes with attenuated expression and 99 genes with elevated expression. Of the latter, 32 genes are related to defense against pathogens (e.g. WRKY33, PR1 and chitinase). Propagation of a virulent strain of the bacterial pathogen Pseudomonas syringae and the fungal pathogen Botrytis cinerea were attenuated in both mutants. Moreover, both mutants accumulated high levels of H2O2. We suggest that CAMTA3 regulates the expression of a set of genes involved in biotic defense responses.",

keywords = "Calcium, Calmodulin, Pathogens, Reactive oxygen species, Signal transduction, Transcriptome",

author = "Yael Galon and Roy Nave and Boyce, {Joy M.} and Dikla Nachmias and Knight, {Marc R.} and Hillel Fromm",

note = "Funding Information: We thank Dr. Aliza Finkler for critical reading of the manuscript, Dr. Ester Feldmesser for bioinformatics assistance; Dr. Guido Sessa and Prof. Amir Sharon for guidance with pathogenicity tests. The research was supported by Grants from the Biotechnology and Biological Sciences Research Council (BBSRC), UK to M.R.K. and the Israel Science Foundation (ISF) to H.F. ",

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doi = "10.1016/j.febslet.2008.02.037",

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AU - Nave, Roy

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AU - Nachmias, Dikla

AU - Knight, Marc R.

AU - Fromm, Hillel

N1 - Funding Information: We thank Dr. Aliza Finkler for critical reading of the manuscript, Dr. Ester Feldmesser for bioinformatics assistance; Dr. Guido Sessa and Prof. Amir Sharon for guidance with pathogenicity tests. The research was supported by Grants from the Biotechnology and Biological Sciences Research Council (BBSRC), UK to M.R.K. and the Israel Science Foundation (ISF) to H.F.

PY - 2008/3/19

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N2 - Calmodulin-binding transcription activator (CAMTA) 3 (also called SR1) is a calmodulin-binding transcription factor in Arabidopsis. Two homozygous T-DNA insertion mutants (camta3-1, camta3-2) showed enhanced spontaneous lesions. Transcriptome analysis of both mutants revealed 6 genes with attenuated expression and 99 genes with elevated expression. Of the latter, 32 genes are related to defense against pathogens (e.g. WRKY33, PR1 and chitinase). Propagation of a virulent strain of the bacterial pathogen Pseudomonas syringae and the fungal pathogen Botrytis cinerea were attenuated in both mutants. Moreover, both mutants accumulated high levels of H2O2. We suggest that CAMTA3 regulates the expression of a set of genes involved in biotic defense responses.

AB - Calmodulin-binding transcription activator (CAMTA) 3 (also called SR1) is a calmodulin-binding transcription factor in Arabidopsis. Two homozygous T-DNA insertion mutants (camta3-1, camta3-2) showed enhanced spontaneous lesions. Transcriptome analysis of both mutants revealed 6 genes with attenuated expression and 99 genes with elevated expression. Of the latter, 32 genes are related to defense against pathogens (e.g. WRKY33, PR1 and chitinase). Propagation of a virulent strain of the bacterial pathogen Pseudomonas syringae and the fungal pathogen Botrytis cinerea were attenuated in both mutants. Moreover, both mutants accumulated high levels of H2O2. We suggest that CAMTA3 regulates the expression of a set of genes involved in biotic defense responses.

KW - Calcium

KW - Calmodulin

KW - Pathogens

KW - Reactive oxygen species

KW - Signal transduction

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Calmodulin-binding transcription activator (CAMTA) 3 mediates biotic defense responses in Arabidopsis

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