Calcification of a porcine valve xenograft during pregnancy - A case report and review of the literature

E. Deviri, M. Yechezkel, L. Levinsky, B. A. Vidne, M. J. Levy

Research output: Contribution to journalArticlepeer-review

Abstract

A 20-year-old woman required urgent replacement of a calcified prosthetic mitral porcine xenograft with a mechanical one during the 32nd week of pregnancy. Five weeks later the patient delivered a normal child. Following delivery the patient refused oral anticoagulant treatment and 7 months later she underwent emergency removal of a prosthetic valve thrombus. Six months later, still refusing anticoagulant treatment, she died of cerebral embolization. We suggest that the replacement of a degenerated biologic valve with another biologic valve should be considered in patients who refuse anticoagulant treatment and that patients with prosthetic xenografts should be kept under close medical follow-up, including echocardiography because of possible accelerated xenograft failure during and/or following pregnancy.

Original languageEnglish
Pages (from-to)266-268
Number of pages3
JournalThoracic and Cardiovascular Surgeon
Volume32
Issue number4
DOIs
StatePublished - 1984

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