Caffeine intoxication: History, clinical features, diagnosis and treatment

Iulian Iancu*, Rael D. Strous

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations


Caffeine is considered to be the most commonly used psychoactive drug in the world and about 80% of adult individuals use caffeine-containing foods and beverages. Coffee is a powerful stimulant and its popularity results from this quality. Due to its ubiquitous use and presumably magical effects, caffeine has been suggested as an important factor in the development of, and also the protection from, cancer, neurological disorders and gallbladder stones. While its stimulant properties are valued phenomena in an achievement-oriented society, caffeine also has deleterious effects and can cause a wide range of side effects, either due to abuse or due to abrupt discontinuation of its use. This review summarizes the data available concerning the syndrome of intoxication (caffeinism) and considers the clinical importance of the phenomenon.

Original languageEnglish
Pages (from-to)147-151
Number of pages5
Issue number2
StatePublished - Feb 2006


  • Adenosine
  • Anxiety disorders
  • Caffeine
  • Intoxication


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