C-reactive protein levels do not correlate with retinal artery occlusion but with atherosclerosis

N. Goldenberg-Cohen; Y. Cohen; Y. Monselise; I. Eldar; R. Axer-Siegel; D. Weinberger; M. Kramer

doi:10.1038/eye.2008.159

C-reactive protein levels do not correlate with retinal artery occlusion but with atherosclerosis

N. Goldenberg-Cohen, Y. Cohen, Y. Monselise, I. Eldar, R. Axer-Siegel, D. Weinberger, M. Kramer

Clinical Departments

Research output: Contribution to journal › Article › peer-review

Abstract

Purpose To determine C-reactive protein (CRP) levels in acute retinal artery occlusion (RAO) and their association with atherosclerotic risk factors.MethodsCRP levels in 16 patients with RAO were compared with levels in 16 age-matched controls at risk of atherosclerosis and 16 young volunteers. Repeated CRP testing was performed 6 years later.ResultsElevated CRP levels (>3 mg/l) and risk factors for atherosclerosis were detected in seven patients in the study group (44%) and nine at-risk controls (56%). On follow-up, CRP levels were reduced in all seven retested patients. Six patients died of vascular events within 5 years, of whom four had high CRP levels during RAO.ConclusionsCRP level correlates with atherosclerosis but it is not significantly elevated in patients with RAO.

Original language	English
Pages (from-to)	785-790
Number of pages	6
Journal	Eye
Volume	23
Issue number	4
DOIs	https://doi.org/10.1038/eye.2008.159
State	Published - Apr 2009

Keywords

Atherosclerosis
C-reactive protein
Retinal artery occlusion
Survival

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10.1038/eye.2008.159

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title = "C-reactive protein levels do not correlate with retinal artery occlusion but with atherosclerosis",

abstract = "Purpose To determine C-reactive protein (CRP) levels in acute retinal artery occlusion (RAO) and their association with atherosclerotic risk factors.MethodsCRP levels in 16 patients with RAO were compared with levels in 16 age-matched controls at risk of atherosclerosis and 16 young volunteers. Repeated CRP testing was performed 6 years later.ResultsElevated CRP levels (>3 mg/l) and risk factors for atherosclerosis were detected in seven patients in the study group (44%) and nine at-risk controls (56%). On follow-up, CRP levels were reduced in all seven retested patients. Six patients died of vascular events within 5 years, of whom four had high CRP levels during RAO.ConclusionsCRP level correlates with atherosclerosis but it is not significantly elevated in patients with RAO.",

keywords = "Atherosclerosis, C-reactive protein, Retinal artery occlusion, Survival",

author = "N. Goldenberg-Cohen and Y. Cohen and Y. Monselise and I. Eldar and R. Axer-Siegel and D. Weinberger and M. Kramer",

note = "Funding Information: This study was presented in part at the Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO), Fort Lauderdale, FL, USA, 2001; Abstract no. 3064; supported by the Ernest and Nusia Gothalf Fund, Tel Aviv University, 1998. We thank Ms. Dorit Karesh for the statistical analysis and Gloria Ginzach, Marian Propp and Melanie Kawe for their editorial and secretarial assistance.",

year = "2009",

month = apr,

doi = "10.1038/eye.2008.159",

language = "אנגלית",

volume = "23",

pages = "785--790",

journal = "Eye",

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T1 - C-reactive protein levels do not correlate with retinal artery occlusion but with atherosclerosis

AU - Goldenberg-Cohen, N.

AU - Cohen, Y.

AU - Monselise, Y.

AU - Eldar, I.

AU - Axer-Siegel, R.

AU - Weinberger, D.

AU - Kramer, M.

N1 - Funding Information: This study was presented in part at the Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO), Fort Lauderdale, FL, USA, 2001; Abstract no. 3064; supported by the Ernest and Nusia Gothalf Fund, Tel Aviv University, 1998. We thank Ms. Dorit Karesh for the statistical analysis and Gloria Ginzach, Marian Propp and Melanie Kawe for their editorial and secretarial assistance.

PY - 2009/4

Y1 - 2009/4

N2 - Purpose To determine C-reactive protein (CRP) levels in acute retinal artery occlusion (RAO) and their association with atherosclerotic risk factors.MethodsCRP levels in 16 patients with RAO were compared with levels in 16 age-matched controls at risk of atherosclerosis and 16 young volunteers. Repeated CRP testing was performed 6 years later.ResultsElevated CRP levels (>3 mg/l) and risk factors for atherosclerosis were detected in seven patients in the study group (44%) and nine at-risk controls (56%). On follow-up, CRP levels were reduced in all seven retested patients. Six patients died of vascular events within 5 years, of whom four had high CRP levels during RAO.ConclusionsCRP level correlates with atherosclerosis but it is not significantly elevated in patients with RAO.

AB - Purpose To determine C-reactive protein (CRP) levels in acute retinal artery occlusion (RAO) and their association with atherosclerotic risk factors.MethodsCRP levels in 16 patients with RAO were compared with levels in 16 age-matched controls at risk of atherosclerosis and 16 young volunteers. Repeated CRP testing was performed 6 years later.ResultsElevated CRP levels (>3 mg/l) and risk factors for atherosclerosis were detected in seven patients in the study group (44%) and nine at-risk controls (56%). On follow-up, CRP levels were reduced in all seven retested patients. Six patients died of vascular events within 5 years, of whom four had high CRP levels during RAO.ConclusionsCRP level correlates with atherosclerosis but it is not significantly elevated in patients with RAO.

KW - Atherosclerosis

KW - C-reactive protein

KW - Retinal artery occlusion

KW - Survival

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C-reactive protein levels do not correlate with retinal artery occlusion but with atherosclerosis

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Keywords

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