TY - JOUR
T1 - Bullous Pemphigoid and Scabies
T2 - Is There an Association?
AU - Rozenblat, Mati
AU - Halaj, Awad
AU - Levi, Assi
AU - Lapidoth, Moshe
AU - Ziv, Michael
N1 - Publisher Copyright:
© 2022 Journal of Drugs in Dermatology. All rights reserved.
PY - 2022/9
Y1 - 2022/9
N2 - Background: Bullous pemphigoid (BP) is an autoimmune subepithelial bullous disease. Several reports suggested an association between BP and scabies. Objective: We aimed to evaluate whether an association between BP and scabies exists. Methods: This is a retrospective matched case-control study. We retrospectively identified BP patients treated in our clinic between January 1, 2009, and December 31, 2016. Each patient was assigned to 3 control subjects (matched by age and sex) treated in our clinic, not due to BP. The study group was examined for a scabies diagnosis within the 3 years prior to BP diagnosis; the control group was examined for a scabies diagnosis 3 years prior to its first visit in our clinic. Results: Fifteen out of the 87 (17.2%) BP patients were diagnosed with scabies within the 3 years prior to their initial BP diagnosis, compared to only 4.2% (11 out of 261) among the control group. The odds ratio of scabies history was 4 times higher among BP patients compared to the control group (OR=4.23; 95% CI: 1.50-11.91, P=0.007). Limitations: A retrospective study design. Conclusions: An association between scabies diagnosis and BP is demonstrated in our study.
AB - Background: Bullous pemphigoid (BP) is an autoimmune subepithelial bullous disease. Several reports suggested an association between BP and scabies. Objective: We aimed to evaluate whether an association between BP and scabies exists. Methods: This is a retrospective matched case-control study. We retrospectively identified BP patients treated in our clinic between January 1, 2009, and December 31, 2016. Each patient was assigned to 3 control subjects (matched by age and sex) treated in our clinic, not due to BP. The study group was examined for a scabies diagnosis within the 3 years prior to BP diagnosis; the control group was examined for a scabies diagnosis 3 years prior to its first visit in our clinic. Results: Fifteen out of the 87 (17.2%) BP patients were diagnosed with scabies within the 3 years prior to their initial BP diagnosis, compared to only 4.2% (11 out of 261) among the control group. The odds ratio of scabies history was 4 times higher among BP patients compared to the control group (OR=4.23; 95% CI: 1.50-11.91, P=0.007). Limitations: A retrospective study design. Conclusions: An association between scabies diagnosis and BP is demonstrated in our study.
UR - http://www.scopus.com/inward/record.url?scp=85138125873&partnerID=8YFLogxK
U2 - 10.36849/JDD.4900
DO - 10.36849/JDD.4900
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
C2 - 36074509
AN - SCOPUS:85138125873
SN - 1545-9616
VL - 21
SP - 1009
EP - 1011
JO - Journal of Drugs in Dermatology
JF - Journal of Drugs in Dermatology
IS - 9
ER -