Brown tumour of hyperparathyroidism in the mandible associated with atypical parathyroid adenoma

Oran Goshen, Sarit Aviel-Ronen, Shay Dori, Yoav P. Talmi

Research output: Contribution to journalArticlepeer-review

Abstract

The brown tumour of hyperparathyroidism is a localized bone tumour and an uncommon manifestation of hyperparathyroidism. A 27-year-old woman presented with a mandibular 8 x 10 cm solid mass diagnosed as central giant cell granuloma. Chemical blood analysis revealed increased serum calcium levels of 12.46 mg/dL and the parathyroid hormone level was 124 pg/dL. The patient underwent surgery with removal of a parathyroid mass. Histologically, this parathyroid tissue was seen to be limited by a fibrous capsule with morphological features consistent with atypical parathyroid adenoma. The mandibular tumour has receded and the patient declined further procedures. This is the first case reported of brown tumour as the primary manifestation of an atypical parathyroid adenoma, a lesion that shares some features with parathyroid carcinoma without the unequivocal properties of malignancy.

Original languageEnglish
Pages (from-to)302-304
Number of pages3
JournalJournal of Laryngology and Otology
Volume114
Issue number4
DOIs
StatePublished - 2000
Externally publishedYes

Keywords

  • Adenoma
  • Giant cell tumours
  • Hyperparathyroidism
  • Parathyroid diseases
  • Parathyroid neoplasms

Fingerprint

Dive into the research topics of 'Brown tumour of hyperparathyroidism in the mandible associated with atypical parathyroid adenoma'. Together they form a unique fingerprint.

Cite this