Bromofluorination of olefins using BrF3; an efficient route for fluoroalkenes and fluoroamines

Revital Sasson, Shlomo Rozen*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

A variety of alkenes and α,β-unsaturated carbonyls were reacted with BrF3 to form vicinal bromofluoro compounds. In most cases, the reactions followed a Markovnikov regioselectivity and anti-addition stereospecifity. They proceeded well even with deactivated olefins in around 70% yield. The bromofluoro compounds served as starting materials for the synthesis of fluoroalkenes and fluoroamines.

Original languageEnglish
Pages (from-to)962-965
Number of pages4
JournalJournal of Fluorine Chemistry
Volume127
Issue number7
DOIs
StatePublished - Jul 2006

Funding

FundersFunder number
United States-Israel Binational Science Foundation

    Keywords

    • BrF
    • Bromofluorination
    • Bromofluoroalkane
    • Fluoroamino acid

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