Breastfeeding and Autoimmunity: A Lesson for Life

Vânia Vieira Borba*, Kassem Sharif, Yehuda Shoenfeld

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Diet is one of the most important environmental exposures in early life. Breast milk is not only a completely adapted nutrition source for the newborn but also an impressive array of immune active molecules that afford protection against infections and shape mucosal immune responses. Decisive imprinting events might be modulated during the first months of life with potential health long-term effects, enhancing the importance of breastfeeding as a major influence on the immune system correct development and modifying disease susceptibility. Current scientific evidence supports the beneficial role of breastfeeding in several immune-mediated diseases, although a few exact pathways are yet to be elucidated.

Original languageEnglish
Title of host publicationMosaic of Autoimmunity
Subtitle of host publicationThe Novel Factors of Autoimmune Diseases
PublisherElsevier
Pages279-287
Number of pages9
ISBN (Electronic)9780128143087
ISBN (Print)9780128143070
DOIs
StatePublished - 13 Feb 2019

Keywords

  • Autoimmune diseases
  • Breastfeeding
  • Human milk
  • Microbiome
  • Prolactin
  • Systemic lupus erythematosus
  • Tolerance

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