Breast enlargement induced by D-penicillamine

Joseph Z. Tchebiner

doi:10.1345/aph.1A229

Breast enlargement induced by D-penicillamine

Joseph Z. Tchebiner^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

OBJECTIVE: To report a patient with reversible breast enlargement due to D-penicillamine treatment for scleroderma. CASE SUMMARY: A 55-year-old white woman developed enlarged breasts during D-penicillamine therapy for scleroderma. The enlargement regressed following discontinuation of the drug, and planned breast reduction surgery was avoided. DISCUSSION: D-Penicillamine has been used in the treatment of various diseases including scleroderma. Breast enlargement has been previously described as a rare adverse effect of this drug. The enlargement subsided following discontinuation of the medication. CONCLUSIONS: Attention is called to this rare adverse effect in an effort to avoid unnecessary diagnostic or therapeutic procedures, including surgery.

Original language	English
Pages (from-to)	444-445
Number of pages	2
Journal	Annals of Pharmacotherapy
Volume	36
Issue number	3
DOIs	https://doi.org/10.1345/aph.1A229
State	Published - 2002
Externally published	Yes

Keywords

Breast enlargement
D-penicillamine
Scleroderma

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10.1345/aph.1A229

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title = "Breast enlargement induced by D-penicillamine",

abstract = "OBJECTIVE: To report a patient with reversible breast enlargement due to D-penicillamine treatment for scleroderma. CASE SUMMARY: A 55-year-old white woman developed enlarged breasts during D-penicillamine therapy for scleroderma. The enlargement regressed following discontinuation of the drug, and planned breast reduction surgery was avoided. DISCUSSION: D-Penicillamine has been used in the treatment of various diseases including scleroderma. Breast enlargement has been previously described as a rare adverse effect of this drug. The enlargement subsided following discontinuation of the medication. CONCLUSIONS: Attention is called to this rare adverse effect in an effort to avoid unnecessary diagnostic or therapeutic procedures, including surgery.",

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AB - OBJECTIVE: To report a patient with reversible breast enlargement due to D-penicillamine treatment for scleroderma. CASE SUMMARY: A 55-year-old white woman developed enlarged breasts during D-penicillamine therapy for scleroderma. The enlargement regressed following discontinuation of the drug, and planned breast reduction surgery was avoided. DISCUSSION: D-Penicillamine has been used in the treatment of various diseases including scleroderma. Breast enlargement has been previously described as a rare adverse effect of this drug. The enlargement subsided following discontinuation of the medication. CONCLUSIONS: Attention is called to this rare adverse effect in an effort to avoid unnecessary diagnostic or therapeutic procedures, including surgery.

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Breast enlargement induced by D-penicillamine

Abstract

Keywords

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