Breakthrough cerebral toxoplasmosis in a patient receiving atovaquone prophylaxis after a hematopoietic stem cell transplantation

Orli Megged; Itamar Shalit; Isaac Yaniv; Jerry Stein; Salvador Fisher; Itzhak Levy

doi:10.1111/j.1399-3046.2007.00891.x

Breakthrough cerebral toxoplasmosis in a patient receiving atovaquone prophylaxis after a hematopoietic stem cell transplantation

Orli Megged, Itamar Shalit, Isaac Yaniv, Jerry Stein, Salvador Fisher, Itzhak Levy^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Abstract

We describe a case of breakthrough cerebral toxoplasmosis during atovaquone therapy in a child who was intolerant of conventional prophylactic regimens after hematopoietic stem cell transplantation. The available data on the efficacy of atovaquone prophylaxis in Toxoplasma sero-positive stem cell transplant recipients remain limited, and other strategies, such as preemptive strategy using toxoplasma PCR or TMP-SMX desensitization should be considered in this setting.

Original language	English
Pages (from-to)	902-905
Number of pages	4
Journal	Pediatric Transplantation
Volume	12
Issue number	8
DOIs	https://doi.org/10.1111/j.1399-3046.2007.00891.x
State	Published - Dec 2008

Keywords

Atovaquone
Encephalitis
HSCT
Toxoplasmosis

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AU - Levy, Itzhak

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Breakthrough cerebral toxoplasmosis in a patient receiving atovaquone prophylaxis after a hematopoietic stem cell transplantation

Abstract

Keywords

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