Brain 18F-FDG-PET: Utility in the diagnosis of dementia and epilepsy

Eyal Lotan; Kent P. Friedman; Tima Davidson; Timothy M. Shepherd

Brain ¹⁸F-FDG-PET: Utility in the diagnosis of dementia and epilepsy

Eyal Lotan^*, Kent P. Friedman, Tima Davidson, Timothy M. Shepherd

^*Corresponding author for this work

Diagnostic Imaging

Research output: Contribution to journal › Review article › peer-review

31 Scopus citations

Abstract

The authors reviewed the two most common current uses of brain ¹⁸F-labeled fluoro-2-deoxyglucose positron emission tomography (FDG-PET) at a large academic medical center. For epilepsy patients considering surgical management, FDG-PET can help localize epileptogenic lesions, discriminate between multiple or discordant EEG or MRI findings, and predict prognosis for post-surgical seizure control. In elderly patients with cognitive impairment, FDG-PET often demonstrates lobar-specific patterns of hypometabolism that suggest particular underlying neurodegenerative pathologies, such as Alzheimer’s disease. FDG-PET of the brain can be a key diagnostic modality and contribute to improved patient care.

Original language	English
Pages (from-to)	178-184
Number of pages	7
Journal	Israel Medical Association Journal
Volume	22
Issue number	3
State	Published - Mar 2020

Keywords

Alzheimer’s disease
Dementia
Epilepsy
F-labeled fluoro-2-deoxyglucose positron emission tomography (FDG-PET)

Cite this

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title = "Brain 18F-FDG-PET: Utility in the diagnosis of dementia and epilepsy",

abstract = "The authors reviewed the two most common current uses of brain 18F-labeled fluoro-2-deoxyglucose positron emission tomography (FDG-PET) at a large academic medical center. For epilepsy patients considering surgical management, FDG-PET can help localize epileptogenic lesions, discriminate between multiple or discordant EEG or MRI findings, and predict prognosis for post-surgical seizure control. In elderly patients with cognitive impairment, FDG-PET often demonstrates lobar-specific patterns of hypometabolism that suggest particular underlying neurodegenerative pathologies, such as Alzheimer{\textquoteright}s disease. FDG-PET of the brain can be a key diagnostic modality and contribute to improved patient care.",

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AB - The authors reviewed the two most common current uses of brain 18F-labeled fluoro-2-deoxyglucose positron emission tomography (FDG-PET) at a large academic medical center. For epilepsy patients considering surgical management, FDG-PET can help localize epileptogenic lesions, discriminate between multiple or discordant EEG or MRI findings, and predict prognosis for post-surgical seizure control. In elderly patients with cognitive impairment, FDG-PET often demonstrates lobar-specific patterns of hypometabolism that suggest particular underlying neurodegenerative pathologies, such as Alzheimer’s disease. FDG-PET of the brain can be a key diagnostic modality and contribute to improved patient care.

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Brain ¹⁸F-FDG-PET: Utility in the diagnosis of dementia and epilepsy

Abstract

Keywords

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