Brain: Body ratio and conceptional age in vascular-induced intrauterine growth retarded rabbits

Shaul Harel; Ephraim Yavin; Avraham Tomer; Yehuda Barak; Itzhak Binderman

doi:10.1016/S0387-7604(85)80004-8

Brain: Body ratio and conceptional age in vascular-induced intrauterine growth retarded rabbits

Shaul Harel^*, Ephraim Yavin, Avraham Tomer, Yehuda Barak, Itzhak Binderman

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Vascular induced intrauterine growth retardation (IUGR) was achieved by total ligation of approximately 30% of the placental vessels to half the fetuses in the last third of gestation in pregnant rabbits. A correlation between brain weight, body weight and head circumference was established in fetuses and rabbit pups in the perinatal period. The brain: body ratio in restricted IUGR animals was significantly higher than their homologous normal controls. A cephalization index based on the brain: body ratio is proposed to assess adverse effects on brain maturity in the presence of IUGR induced by placental insufficiency.

Original language	English
Pages (from-to)	575-579
Number of pages	5
Journal	Brain and Development
Volume	7
Issue number	6
DOIs	https://doi.org/10.1016/S0387-7604(85)80004-8
State	Published - 1985

Keywords

Brain: body ratio
intrauterine growth retardation
rabbit

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10.1016/S0387-7604(85)80004-8

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title = "Brain: Body ratio and conceptional age in vascular-induced intrauterine growth retarded rabbits",

abstract = "Vascular induced intrauterine growth retardation (IUGR) was achieved by total ligation of approximately 30% of the placental vessels to half the fetuses in the last third of gestation in pregnant rabbits. A correlation between brain weight, body weight and head circumference was established in fetuses and rabbit pups in the perinatal period. The brain: body ratio in restricted IUGR animals was significantly higher than their homologous normal controls. A cephalization index based on the brain: body ratio is proposed to assess adverse effects on brain maturity in the presence of IUGR induced by placental insufficiency.",

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author = "Shaul Harel and Ephraim Yavin and Avraham Tomer and Yehuda Barak and Itzhak Binderman",

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AU - Harel, Shaul

AU - Yavin, Ephraim

AU - Tomer, Avraham

AU - Barak, Yehuda

AU - Binderman, Itzhak

PY - 1985

Y1 - 1985

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AB - Vascular induced intrauterine growth retardation (IUGR) was achieved by total ligation of approximately 30% of the placental vessels to half the fetuses in the last third of gestation in pregnant rabbits. A correlation between brain weight, body weight and head circumference was established in fetuses and rabbit pups in the perinatal period. The brain: body ratio in restricted IUGR animals was significantly higher than their homologous normal controls. A cephalization index based on the brain: body ratio is proposed to assess adverse effects on brain maturity in the presence of IUGR induced by placental insufficiency.

KW - Brain: body ratio

KW - intrauterine growth retardation

KW - rabbit

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JO - Brain and Development

JF - Brain and Development

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ER -

Brain: Body ratio and conceptional age in vascular-induced intrauterine growth retarded rabbits

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Keywords

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