TY - JOUR
T1 - Brain
T2 - Body ratio and conceptional age in vascular-induced intrauterine growth retarded rabbits
AU - Harel, Shaul
AU - Yavin, Ephraim
AU - Tomer, Avraham
AU - Barak, Yehuda
AU - Binderman, Itzhak
PY - 1985
Y1 - 1985
N2 - Vascular induced intrauterine growth retardation (IUGR) was achieved by total ligation of approximately 30% of the placental vessels to half the fetuses in the last third of gestation in pregnant rabbits. A correlation between brain weight, body weight and head circumference was established in fetuses and rabbit pups in the perinatal period. The brain: body ratio in restricted IUGR animals was significantly higher than their homologous normal controls. A cephalization index based on the brain: body ratio is proposed to assess adverse effects on brain maturity in the presence of IUGR induced by placental insufficiency.
AB - Vascular induced intrauterine growth retardation (IUGR) was achieved by total ligation of approximately 30% of the placental vessels to half the fetuses in the last third of gestation in pregnant rabbits. A correlation between brain weight, body weight and head circumference was established in fetuses and rabbit pups in the perinatal period. The brain: body ratio in restricted IUGR animals was significantly higher than their homologous normal controls. A cephalization index based on the brain: body ratio is proposed to assess adverse effects on brain maturity in the presence of IUGR induced by placental insufficiency.
KW - Brain: body ratio
KW - intrauterine growth retardation
KW - rabbit
UR - http://www.scopus.com/inward/record.url?scp=0022396180&partnerID=8YFLogxK
U2 - 10.1016/S0387-7604(85)80004-8
DO - 10.1016/S0387-7604(85)80004-8
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AN - SCOPUS:0022396180
SN - 0387-7604
VL - 7
SP - 575
EP - 579
JO - Brain and Development
JF - Brain and Development
IS - 6
ER -