Brain activation associated with practiced left hand mirror writing

T. Kushnir*, Y. Arzouan, A. Karni, D. Manor

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Mirror writing occurs in healthy children, in various pathologies and occasionally in healthy adults. There are only scant experimental data on the underlying brain processes.Eight, right-handed, healthy young adults were scanned (BOLD-fMRI) before and after practicing left-hand mirror-writing (lh-MW) over seven sessions. They wrote dictated words, using either the right hand with regularly oriented writing or lh-MW. An MRI compatible stylus-point recording system was used and online visual feedback was provided.Practice resulted in increased speed and readability of lh-MW but the number of movement segments was unchanged. Post-training signal increases occurred in visual, right lateral and medial premotor areas, and in right anterior and posterior peri-sylvian areas corresponding to language areas.These results suggest that lh-MW may constitute a latent ability that can be reinstated by a relatively brief practice experience. Concurrently, right hemisphere language processing areas may emerge, reflecting perhaps a reduction in trans-hemispheric suppression.

Original languageEnglish
Pages (from-to)38-46
Number of pages9
JournalBrain and Language
Issue number1
StatePublished - Apr 2013
Externally publishedYes


FundersFunder number
Council for Scientific and Technological Cooperation between France & Israel


    • FMRI
    • MRI compatible kinematics recording
    • Mirror writing
    • Real-time visual feedback device


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