Botrytis cinerea BcCDI1 protein triggers both plant cell death and immune response

Wenjun Zhu, Huange Dong, Ran Xu*, Jingmao You*, Da Zhong Yan, Chao Xiong, Jing Wu, Kai Bi*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Cell death-inducing proteins (CDIPs) play important roles in the infection of Botrytis cinerea, a broad host-range necrotrophic phytopathogen. Here, we show that the secreted protein BcCDI1 (Cell Death Inducing 1) can cause necrosis in tobacco leaves and at the same time elicit plant defense. The transcription of Bccdi1 was induced at the infection stage. Deletion or overexpression of Bccdi1 resulted in no notable change in disease lesion on bean, tobacco, and Arabidopsis leaves, indicating that Bccdi1 has no effect on the final outcome of B. cinerea infection. Furthermore, the plant receptor-like kinases BAK1 and SOBIR1 are required to transduce the cell death-promoting signal induced by BcCDI1. These findings suggest that BcCDI1 is possibly recognized by plant receptors and then induces plant cell death.

Original languageEnglish
Article number1136463
JournalFrontiers in Plant Science
StatePublished - 2023
Externally publishedYes


  • BcCDI1
  • Botrytis cinerea
  • CDIPs
  • elicitor
  • plant defense


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