BOPINDOLOL: LONG‐TERM EFFECTS ON BLOOD PRESSURE, RENAL FUNCTION, PLASMA RENIN ACTIVITY, AND PLASMA ALDOSTERONE IN MILD‐TO‐MODERATE ESSENTIAL HYPERTENSION

J. SHOHAT; M. MODAN; J. B. ROSENFELD

doi:10.1111/j.1472-8206.1989.tb00030.x

BOPINDOLOL: LONG‐TERM EFFECTS ON BLOOD PRESSURE, RENAL FUNCTION, PLASMA RENIN ACTIVITY, AND PLASMA ALDOSTERONE IN MILD‐TO‐MODERATE ESSENTIAL HYPERTENSION

J. SHOHAT, M. MODAN, J. B. ROSENFELD

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Abstract

Summary— Bopindolol was given to hypertensive patients in a single daily dose ranging from 1 to 4 mg. In 86.7% of the patients diastolic blood pressure was reduced by 10 mmHg or more, or lowered to below 90 mmHg, already during the first 4 wk of treatment. Inulin clearance decreased by 10%; PAH and creatinine clearance, blood urea nitrogen, and serum creatinine were unchanged. 1989 Société Française de Pharmacologie et de Thérapeutique

Original language	English
Pages (from-to)	53-58
Number of pages	6
Journal	Fundamental and Clinical Pharmacology
Volume	3
Issue number	1
DOIs	https://doi.org/10.1111/j.1472-8206.1989.tb00030.x
State	Published - 1989

Keywords

bopindolol
glomerular filtration rate
hypertension
plasma aldosterone
plasma renin activity
renal blood flow

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10.1111/j.1472-8206.1989.tb00030.x

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title = "BOPINDOLOL: LONG‐TERM EFFECTS ON BLOOD PRESSURE, RENAL FUNCTION, PLASMA RENIN ACTIVITY, AND PLASMA ALDOSTERONE IN MILD‐TO‐MODERATE ESSENTIAL HYPERTENSION",

abstract = "Summary— Bopindolol was given to hypertensive patients in a single daily dose ranging from 1 to 4 mg. In 86.7% of the patients diastolic blood pressure was reduced by 10 mmHg or more, or lowered to below 90 mmHg, already during the first 4 wk of treatment. Inulin clearance decreased by 10%; PAH and creatinine clearance, blood urea nitrogen, and serum creatinine were unchanged. 1989 Soci{\'e}t{\'e} Fran{\c c}aise de Pharmacologie et de Th{\'e}rapeutique",

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year = "1989",

doi = "10.1111/j.1472-8206.1989.tb00030.x",

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T2 - LONG‐TERM EFFECTS ON BLOOD PRESSURE, RENAL FUNCTION, PLASMA RENIN ACTIVITY, AND PLASMA ALDOSTERONE IN MILD‐TO‐MODERATE ESSENTIAL HYPERTENSION

AU - SHOHAT, J.

AU - MODAN, M.

AU - ROSENFELD, J. B.

PY - 1989

Y1 - 1989

N2 - Summary— Bopindolol was given to hypertensive patients in a single daily dose ranging from 1 to 4 mg. In 86.7% of the patients diastolic blood pressure was reduced by 10 mmHg or more, or lowered to below 90 mmHg, already during the first 4 wk of treatment. Inulin clearance decreased by 10%; PAH and creatinine clearance, blood urea nitrogen, and serum creatinine were unchanged. 1989 Société Française de Pharmacologie et de Thérapeutique

AB - Summary— Bopindolol was given to hypertensive patients in a single daily dose ranging from 1 to 4 mg. In 86.7% of the patients diastolic blood pressure was reduced by 10 mmHg or more, or lowered to below 90 mmHg, already during the first 4 wk of treatment. Inulin clearance decreased by 10%; PAH and creatinine clearance, blood urea nitrogen, and serum creatinine were unchanged. 1989 Société Française de Pharmacologie et de Thérapeutique

KW - bopindolol

KW - glomerular filtration rate

KW - hypertension

KW - plasma aldosterone

KW - plasma renin activity

KW - renal blood flow

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JO - Fundamental and Clinical Pharmacology

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BOPINDOLOL: LONG‐TERM EFFECTS ON BLOOD PRESSURE, RENAL FUNCTION, PLASMA RENIN ACTIVITY, AND PLASMA ALDOSTERONE IN MILD‐TO‐MODERATE ESSENTIAL HYPERTENSION

Abstract

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