TY - JOUR
T1 - Bone scans in the diagnosis of bone crisis in patients who have Gaucher disease
AU - Katz, K.
AU - Mechlis-Frish, S.
AU - Cohen, I. J.
AU - Horev, G.
AU - Zaizov, R.
AU - Lubin, E.
PY - 1991
Y1 - 1991
N2 - Of thirty-four occurrences of bone pain in seventeen children and young adults who had type-I Gaucher disease, twenty-five were finally diagnosed as bone crises. On the basis of a bone scan with technetium-99m methylene diphosphonate, a correct diagnosis of bone crisis was made for twenty-three occurrences, with a sensitivity of 0.92. At the onset of a crisis, the bone scan typically showed decreased uptake of radionuclide at the involved site. After six weeks, a repeat bone scan of the long bones showed a ring of increased uptake surrounding an area of decreased uptake. At six months, the appearance of the bones on the radionuclide scan was normal.
AB - Of thirty-four occurrences of bone pain in seventeen children and young adults who had type-I Gaucher disease, twenty-five were finally diagnosed as bone crises. On the basis of a bone scan with technetium-99m methylene diphosphonate, a correct diagnosis of bone crisis was made for twenty-three occurrences, with a sensitivity of 0.92. At the onset of a crisis, the bone scan typically showed decreased uptake of radionuclide at the involved site. After six weeks, a repeat bone scan of the long bones showed a ring of increased uptake surrounding an area of decreased uptake. At six months, the appearance of the bones on the radionuclide scan was normal.
UR - http://www.scopus.com/inward/record.url?scp=0025896554&partnerID=8YFLogxK
U2 - 10.2106/00004623-199173040-00006
DO - 10.2106/00004623-199173040-00006
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AN - SCOPUS:0025896554
SN - 0021-9355
VL - 73
SP - 513
EP - 517
JO - Journal of Bone and Joint Surgery - Series A
JF - Journal of Bone and Joint Surgery - Series A
IS - 4
ER -