Bone marrow cell populations mimicking common acute lymphoblastic leukemia in infants with stage iv-s neuroblastoma

M. Mandel, G. Rechavi, Y. Neumann, M. Biniaminov, F. Brok-Simoni, Y. Bojanover, Y. Burstein, I. Ben-Bassat, B. Ramot

Research output: Contribution to journalArticlepeer-review

Abstract

Immunophenotyping of bone marrow mononuclear cells of 2 infants with stage IV-S neuroblastoma revealed the presence of many lymphoblasts and immature lymphocytes. Immunophenotyping showed that a high percentage of bone marrow cells were positive for the HLA-DR, CD19, CD20 and CD10 phenotype, similar to common acute lymphoblastic leukemia cells. Within 6 months of follow-up, without any treatment, complete regression of the tumors was observed. The coexistence of these two unusual populations will be discussed.

Original languageEnglish
Pages (from-to)86-89
Number of pages4
JournalActa Haematologica
Volume86
Issue number2
DOIs
StatePublished - 1991

Keywords

  • Acute lymphoblastic leukemia
  • Cd10
  • Enkephalins
  • Immature lymphoid cells
  • Neuroblastoma

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