Bone-implant-contact and new bone formation around implants placed in FDB blocks compared to placement at the adjunction of particulate FDB

Karen Anavi Lev, Liat Chaushu, Frank Schwarz, Zvi Artzi

Research output: Contribution to journalArticlepeer-review

Abstract

Background: The efficacy of human freeze-dried bone (h-FDB) as particulate vs block forms as a proper onlay augmented bone graft material to accommodate implants is undetermined. Purpose: To evaluate osseointegration and new bone formation at implants placed in FDB blocks (BL group) and those at the adjunction of particulate FDB (PR group). Materials and Methods: Twelve pairs of h-FDB blocks were stabilized bilaterally to the calvaria of 12 rabbits. Twenty-four SLA implants were placed at the remodeled grafted blocks, 4 months later. A circumferential gap was created around one implant in each pair and packed with particulate h-FDB. Section biopsies were obtained at 2-month post implant placement (6 months post-block grafting). Bone-to-implant contact (BIC) and bone-area fraction (BAF) were histomorphometrically calculated. Results: The mean BIC was 34.4% and 33.5% for the BL and PR groups, respectively. The mean BAF was 23.9% and 26.4% for the corresponding groups, respectively. Osseointegration and newly formed bone were evident mostly between the threaded portions of the implants in proximity to the host rabbit calvaria compared to its cervical neck. Conclusion: The particulate and the cancellous block h-FDB forms yielded similar BIC and BAF outcome. Full revascularization/revitalization is questioned.

Original languageEnglish
Pages (from-to)21-28
Number of pages8
JournalClinical Implant Dentistry and Related Research
Volume22
Issue number1
DOIs
StatePublished - 1 Feb 2020

Keywords

  • allogeneic bone block
  • allografts
  • bone grafts
  • bone-implant contact
  • freeze dried bone
  • osseointegration

Fingerprint

Dive into the research topics of 'Bone-implant-contact and new bone formation around implants placed in FDB blocks compared to placement at the adjunction of particulate FDB'. Together they form a unique fingerprint.

Cite this