TY - JOUR
T1 - Bone age assessments by quantitative ultrasound (SonicBone) and hand X-ray based methods are comparable
AU - Rachmiel, Marianna
AU - Naugolni, Larisa
AU - Mazor-Aronovitch, Kineret
AU - Koren-Morag, Nira
AU - Bistritzer, Tzvi
N1 - Publisher Copyright:
© 2017, Israel Medical Association. All rights reserved.
PY - 2017/9
Y1 - 2017/9
N2 - Background: Bone maturation is currently assessed by subjective and automated radiography. Objectives: To evaluate the concordance and reproducibility of a quantitative ultrasound (QUS) based device versus X-ray based methods. Methods: The study population comprised 150 children, 76 males, 4–17 years of age. X-ray scans were evaluated according to wrist, carpal, and phalanx areas for bone age. QUS was performed by the the BAUS™ device (SonicBone, Rishon Lezion, Israel), using speed-of-sound (SOS) and distance attenuation factor (ATN) in similar areas. Data from 100 subjects were used to establish the device conversion equation, and 50 measurements were assigned to assess inter-modality agreement. Results: BAUS showed high repeatability performance, 0.73% relative standard deviation for SOS and 3.5% for ATN. R2 for the conversion equation including gender, SOS, and ATN was 0.80 for all methods (P < 0.001). There was no significant bias in bone age assessments. Conclusions: Bone age assessment by SonicBone is comparable to the assessment by X-ray based methods.
AB - Background: Bone maturation is currently assessed by subjective and automated radiography. Objectives: To evaluate the concordance and reproducibility of a quantitative ultrasound (QUS) based device versus X-ray based methods. Methods: The study population comprised 150 children, 76 males, 4–17 years of age. X-ray scans were evaluated according to wrist, carpal, and phalanx areas for bone age. QUS was performed by the the BAUS™ device (SonicBone, Rishon Lezion, Israel), using speed-of-sound (SOS) and distance attenuation factor (ATN) in similar areas. Data from 100 subjects were used to establish the device conversion equation, and 50 measurements were assigned to assess inter-modality agreement. Results: BAUS showed high repeatability performance, 0.73% relative standard deviation for SOS and 3.5% for ATN. R2 for the conversion equation including gender, SOS, and ATN was 0.80 for all methods (P < 0.001). There was no significant bias in bone age assessments. Conclusions: Bone age assessment by SonicBone is comparable to the assessment by X-ray based methods.
KW - BAUS™
KW - Growth
KW - Short stature
KW - Skeletal maturation
KW - SonicBone
UR - http://www.scopus.com/inward/record.url?scp=85030776734&partnerID=8YFLogxK
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AN - SCOPUS:85030776734
SN - 1565-1088
VL - 19
SP - 533
EP - 537
JO - Israel Medical Association Journal
JF - Israel Medical Association Journal
IS - 9
ER -