Body temperature - A marker of infarct size in the era of early reperfusion

Itsik Ben-Dor, Moti Haim, Eldad Rechavia, Daniel Murininkas, Merav Nahon, Daniella Harell, Avital Porter, Zaza Iakobishvili, Erez Scapa, Alexander Battler, David Hasdai

Research output: Contribution to journalArticlepeer-review

Abstract

We measured body temperature in 40 consecutive patients treated for a first ST elevation acute myocardial infarction (AMI) with primary percutaneous coronary interventions. Left ventricular function was assessed by echocardiography, and blood samples were drawn for highly sensitive C-reactive protein (hs-CRP), white blood cell (WBC) count, fibrinogen, creatine kinase (CK), and cardiac troponin I levels (cTnI). The median (25th, 75th quartiles) peak 24-hour temperature was 37.4°C (36.9°C, 37.6°C). Variables significantly associated with peak 24-hour temperature were CK (p = 0.01, r = 0.42), wall motion index (p = 0.01, r = 0.41), hs-CRP (p = 0.01, r = 0.41), and cTnI (p = 0.03, r = 0.35). There was no significant correlation between peak 24-hour temperature and WBC count (p = 0.39, r = 0.14) and fibrinogen (p = 0.12, r = 0.21). Thus, peak 24-hour body temperature after ST elevation AMI probably reflects infarct size rather than a nonspecific inflammatory response.

Original languageEnglish
Pages (from-to)169-173
Number of pages5
JournalCardiology
Volume103
Issue number4
DOIs
StatePublished - 2005

Keywords

  • Body temperature
  • Fever
  • Infarct size
  • Inflammation
  • Myocardial infarction

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