TY - JOUR
T1 - Body temperature - A marker of infarct size in the era of early reperfusion
AU - Ben-Dor, Itsik
AU - Haim, Moti
AU - Rechavia, Eldad
AU - Murininkas, Daniel
AU - Nahon, Merav
AU - Harell, Daniella
AU - Porter, Avital
AU - Iakobishvili, Zaza
AU - Scapa, Erez
AU - Battler, Alexander
AU - Hasdai, David
PY - 2005
Y1 - 2005
N2 - We measured body temperature in 40 consecutive patients treated for a first ST elevation acute myocardial infarction (AMI) with primary percutaneous coronary interventions. Left ventricular function was assessed by echocardiography, and blood samples were drawn for highly sensitive C-reactive protein (hs-CRP), white blood cell (WBC) count, fibrinogen, creatine kinase (CK), and cardiac troponin I levels (cTnI). The median (25th, 75th quartiles) peak 24-hour temperature was 37.4°C (36.9°C, 37.6°C). Variables significantly associated with peak 24-hour temperature were CK (p = 0.01, r = 0.42), wall motion index (p = 0.01, r = 0.41), hs-CRP (p = 0.01, r = 0.41), and cTnI (p = 0.03, r = 0.35). There was no significant correlation between peak 24-hour temperature and WBC count (p = 0.39, r = 0.14) and fibrinogen (p = 0.12, r = 0.21). Thus, peak 24-hour body temperature after ST elevation AMI probably reflects infarct size rather than a nonspecific inflammatory response.
AB - We measured body temperature in 40 consecutive patients treated for a first ST elevation acute myocardial infarction (AMI) with primary percutaneous coronary interventions. Left ventricular function was assessed by echocardiography, and blood samples were drawn for highly sensitive C-reactive protein (hs-CRP), white blood cell (WBC) count, fibrinogen, creatine kinase (CK), and cardiac troponin I levels (cTnI). The median (25th, 75th quartiles) peak 24-hour temperature was 37.4°C (36.9°C, 37.6°C). Variables significantly associated with peak 24-hour temperature were CK (p = 0.01, r = 0.42), wall motion index (p = 0.01, r = 0.41), hs-CRP (p = 0.01, r = 0.41), and cTnI (p = 0.03, r = 0.35). There was no significant correlation between peak 24-hour temperature and WBC count (p = 0.39, r = 0.14) and fibrinogen (p = 0.12, r = 0.21). Thus, peak 24-hour body temperature after ST elevation AMI probably reflects infarct size rather than a nonspecific inflammatory response.
KW - Body temperature
KW - Fever
KW - Infarct size
KW - Inflammation
KW - Myocardial infarction
UR - http://www.scopus.com/inward/record.url?scp=21044451309&partnerID=8YFLogxK
U2 - 10.1159/000084589
DO - 10.1159/000084589
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AN - SCOPUS:21044451309
SN - 0008-6312
VL - 103
SP - 169
EP - 173
JO - Cardiology
JF - Cardiology
IS - 4
ER -
