B‐N‐acetyl hexosaminidase (B‐NAH) serum levels after endotoxin administration into the portal vein in the rat

E. Scapa, R. Orda, M. Neuman, J. Sayfan, J. Abramovici, J. Eshchar

Research output: Contribution to journalArticlepeer-review

Abstract

ABSTRACT— Endotoxin was injected directly into the portal vein in rats with and without common bile duct (CBD) ligation. B‐N‐acetyl hexosaminidase (B‐NAH) activity levels in the serum were found to be significantly elevated 24 h later in both groups. Serum bile acid levels were found to be significantly higher in the endotoxin‐injected groups of rats compared to controls. Thus, endotoxin, as well as bile acids, may cause damage to Kupffer cell membranes, resulting in accumulation of B‐NAH in rat serum.

Original languageEnglish
Pages (from-to)39-41
Number of pages3
JournalLiver
Volume11
Issue number1
DOIs
StatePublished - Feb 1991

Keywords

  • B‐N‐acetyl hexosaminidase
  • endotoxin
  • portal vein

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