TY - JOUR
T1 - Blood invasiveness of Salmonella enterica as a function of age and serotype
AU - Weinberger, M.
AU - Andorn, N.
AU - Agmon, V.
AU - Cohen, D.
AU - Shohat, T.
AU - Pitlik, S. D.
PY - 2004/12
Y1 - 2004/12
N2 - We explored the dual influence of the patient's age and the infecting serotype on the blood invasiveness patterns of non-Typhi Salmonella enterica (NTS). Blood invasiveness ratio (BIR) was calculated as the ratio between the number of blood and blood+stool isolates. Analysis of 14951 NTS isolates showed that the BIR increased drastically above the age of 60 years, reaching levels 3.5-7 times higher compared to age group <2 years. Different patterns of age-related invasiveness were observed for the five most common NTS serotypes (Enteritidis, Typhimurium, Virchow, Hadar, Infantis). Among children <2 years, the BIR was highest for serotype Virchow and lowest for serotype Hadar, while in persons ≥60 years it was highest for serotypes Enteritidis and lowest for serotype Infantis. The tendency of NTS serotypes to invade the bloodstream was significantly influenced by the patient's age, however the impact of age differed for various NTS serotypes.
AB - We explored the dual influence of the patient's age and the infecting serotype on the blood invasiveness patterns of non-Typhi Salmonella enterica (NTS). Blood invasiveness ratio (BIR) was calculated as the ratio between the number of blood and blood+stool isolates. Analysis of 14951 NTS isolates showed that the BIR increased drastically above the age of 60 years, reaching levels 3.5-7 times higher compared to age group <2 years. Different patterns of age-related invasiveness were observed for the five most common NTS serotypes (Enteritidis, Typhimurium, Virchow, Hadar, Infantis). Among children <2 years, the BIR was highest for serotype Virchow and lowest for serotype Hadar, while in persons ≥60 years it was highest for serotypes Enteritidis and lowest for serotype Infantis. The tendency of NTS serotypes to invade the bloodstream was significantly influenced by the patient's age, however the impact of age differed for various NTS serotypes.
UR - http://www.scopus.com/inward/record.url?scp=10444223068&partnerID=8YFLogxK
U2 - 10.1017/S0950268803001109
DO - 10.1017/S0950268803001109
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AN - SCOPUS:10444223068
SN - 0950-2688
VL - 132
SP - 1023
EP - 1028
JO - Epidemiology and Infection
JF - Epidemiology and Infection
IS - 6
ER -