Blood invasiveness of Salmonella enterica as a function of age and serotype

M. Weinberger*, N. Andorn, V. Agmon, D. Cohen, T. Shohat, S. D. Pitlik

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


We explored the dual influence of the patient's age and the infecting serotype on the blood invasiveness patterns of non-Typhi Salmonella enterica (NTS). Blood invasiveness ratio (BIR) was calculated as the ratio between the number of blood and blood+stool isolates. Analysis of 14951 NTS isolates showed that the BIR increased drastically above the age of 60 years, reaching levels 3.5-7 times higher compared to age group <2 years. Different patterns of age-related invasiveness were observed for the five most common NTS serotypes (Enteritidis, Typhimurium, Virchow, Hadar, Infantis). Among children <2 years, the BIR was highest for serotype Virchow and lowest for serotype Hadar, while in persons ≥60 years it was highest for serotypes Enteritidis and lowest for serotype Infantis. The tendency of NTS serotypes to invade the bloodstream was significantly influenced by the patient's age, however the impact of age differed for various NTS serotypes.

Original languageEnglish
Pages (from-to)1023-1028
Number of pages6
JournalEpidemiology and Infection
Issue number6
StatePublished - Dec 2004


Dive into the research topics of 'Blood invasiveness of Salmonella enterica as a function of age and serotype'. Together they form a unique fingerprint.

Cite this